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Technology OverviewRamification Amplification Method: With our RAM technology, a billion copies of a gene sequence can quickly and accurately be created (super-exponential amplification), in turn increasing discrimination power up to 1000 fold above current methods. Unlike other amplification techniques that require multiple cycles of alternating temperatures, RAM is an isothermal process that operates at a single temperature of 30°C. Hybridization Signal Amplification Method: HSAM is an elegantly simple signal amplification method that takes advantage of some of the unique structural capabilities of nucleic acids. Conceptually, HSAM can be thought of as a variation on traditional probe network signal amplification schemes, updated by incorporation of cutting-edge nanostructure concepts. HSAM can be used to detect nucleic acids, proteins, or other small molecules that might typically be measured by immunoassay. Read more... Advantages of RAM/HSAM: RAM/HSAM have sufficient sensitivity and accuracy to detect Single Nucleotide Polymorphisms (SNPs) and even single molecules of DNA, RNA or proteins without amplification by PCR. This highly sensitive, isothermal amplification platform offers multiple advantages over current amplification techniques. Read more...
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